UnLtd Blogs - allostatic load

Dr Serani's 6 Myths About Stress

Tue, 25 Apr 2006 13:33:22 +0000

Psychologist Dr Deborah Serani dispels six myths about stress in the hope of promoting greater understanding. It sounds a lot like being aware of the allostatic load of your life. I've borrowed this following explanation of allostasis from Dr. Salt's summary of a classic paper:

[stress has] many mechanisms, but among the most prominent are the manifestations of physiological stress responses as a result of living and working conditions, inter-personal conflict, as well as the sense of control of one’s environment and optimism/pessimism toward the future. "Allostatic load" refers to the cost of adaptation to a stressful environment, which elicits repeated and sometimes prolonged adaptive responses ("allostasis") that preserve homeostasis in the short run but can cause wear- and-tear on the body and brain. Functional symptoms and syndromes, decreased cognitive function during aging, abdominal obesity, increased risk for hypertension and cardiovascular disease, insulin-dependent diabetes and decreased immune responses are all manifestations of allostatic load.
We have powerful ways of modulating the harmful output of the stress response systems that include belief systems and behaviors. An important quote attributed to Dr. McEwen is, "We must also remember that the biggest problems for the human race in the future are those associated with our own behavior and misbehavior and the impact of the social and physical environment on our bodies and brains."

Allostasis, Sleep and Happiness

Fri, 03 Mar 2006 11:55:58 +0000

Following on from allostasis and happiness I've been thinking about the contribution of sleep to allostasis (and therefore, well-being). The Times carried a summary of El-Sheik's research into sleep quality in children. The more that children are exposed to parental conflicts, the worse they sleep. And, the worse children sleep, the more likely they are to be tired when awake, have difficulty focusing and be irritable and badly behaved. All of which sounds like it could make a contribution to a diagnosis of ADHD, particularly the need to have the behaviour documented in a variety of settings. And, as the children would be tired for most of the day, I think that that criterion would be met.

I wrote about the diabetic children with uncontrolled ketoacidosis who prompted Salvador Minuchin to say that "behavioral events among family members can be measured in the bloodstream of other family members". It seems as if that could also be adapted to "behavioural events among family members can be measured in the diagnoses of other family members".

Allostasis and Happiness

Thu, 02 Mar 2006 17:47:00 +0000

I've been reading a lot about allostasis and allostatic load lately. Primarily because I am trying to understand where happiness and its beneficial effects fit in. Leading advocates of the concept claim that it makes sense of why some societies (such as the UK, the rest of Europe and the US) are experiencing a surge in the numbers of people who are developing obsesity, metabolic disorders (e.g., Syndrome X or type II diabetes) or addictions. At its highest level, allostasis implies that social policies have a critical impact on how we experience our lives, and therefore influence our resilience and ability to withstand disease and to recover from illness.

I've borrowed this following explanation of allostasis from Dr. Salt's summary of a classic paper:

[stress has] many mechanisms, but among the most prominent are the manifestations of physiological stress responses as a result of living and working conditions, inter-personal conflict, as well as the sense of control of one�s environment and optimism/pessimism toward the future. "Allostatic load" refers to the cost of adaptation to a stressful environment, which elicits repeated and sometimes prolonged adaptive responses ("allostasis") that preserve homeostasis in the short run but can cause wear- and-tear on the body and brain. Functional symptoms and syndromes, decreased cognitive function during aging, abdominal obesity, increased risk for hypertension and cardiovascular disease, insulin-dependent diabetes and decreased immune responses are all manifestations of allostatic load.